Hacettepe University – MIYELOID

Myeloid-Derived Suppressor Cells (MDSCs) are formed when the bone marrow allows the immature cells needed after chronic inflammation and/or acute inflammation to enter circulation and these cells gain immune suppression ability. Within the scope of this investigation, the distribution and concentration of sub-populations of MDSCs within peripheral blood were determined using the pre-flight and post-flight blood samples taken from TUA’s astronaut were the effect of radiation exposure due to the suborbital spaceflight was analyzed. For the first time, myeloid-derived suppressor cells in peripheral blood samples of a suborbital spaceflight participant after radiation exposure were analyzed. By understanding the characteristics and function of MDSCs after a spaceflight, investigators are hoping to develop therapeutic interventions for both terrestrial and space applications.